AMINACRINE HYDROCHLORIDE Meaning and
Definition
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Aminacrine Hydrochloride is a pharmaceutical compound that is primarily used as an antitumor agent or as a research tool for studying DNA structure and function. It is classified as a synthetic heterocyclic compound belonging to the acridine family.
Aminacrine Hydrochloride is commonly administered in the form of a hydrochloride salt, which allows for improved solubility in water. It is typically available in the form of a crystalline powder or a yellowish solid. This compound exhibits strong fluorescence properties, which make it particularly useful for various applications in biological research.
As an antitumor agent, Aminacrine Hydrochloride works by interfering with the replication and transcription processes of DNA in cancer cells. This inhibition leads to cell cycle arrest and ultimately induces programmed cell death (apoptosis). The compound has shown efficacy against a range of cancers, including lung, breast, and leukemia.
Furthermore, Aminacrine Hydrochloride is often utilized as a fluorescent probe in laboratories for studying nucleic acids, such as DNA and RNA. It can be used to stain nucleic acids, facilitating their visualization and analysis under fluorescence microscopy. Additionally, the compound can intercalate into the DNA helix, disrupting its structure and affecting the interaction with other molecules involved in DNA function.
Overall, Aminacrine Hydrochloride holds significant value in both the medical and scientific fields due to its antitumor properties and its ability to serve as a fluorescent dye for investigating DNA structure and function.
Common Misspellings for AMINACRINE HYDROCHLORIDE
- zminacrine hydrochloride
- sminacrine hydrochloride
- wminacrine hydrochloride
- qminacrine hydrochloride
- aninacrine hydrochloride
- akinacrine hydrochloride
- ajinacrine hydrochloride
- amunacrine hydrochloride
- amjnacrine hydrochloride
- amknacrine hydrochloride
- amonacrine hydrochloride
- am9nacrine hydrochloride
- am8nacrine hydrochloride
- amibacrine hydrochloride
- amimacrine hydrochloride
- amijacrine hydrochloride
- amihacrine hydrochloride
- aminzcrine hydrochloride
- aminscrine hydrochloride
- aminwcrine hydrochloride
Etymology of AMINACRINE HYDROCHLORIDE
The word "Aminacrine" is derived from the combination of two elements. The first part, "Amini-", is derived from "amino", which refers to the presence of an amino group (-NH2) in the chemical compound. The second part, "-crine", is derived from the Greek word "krinein" which means "to separate" or "to secrete".
The word "Hydrochloride" is a combination of "hydro-" derived from the Greek word for water, and "chloride" derived from the chemical element chlorine. "Hydro-" indicates the presence of a hydrogen atom, while "chloride" signifies the compound contains chlorine in the form of an ionic bond with another element or molecule.
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