How Do You Spell ANTIKINASE?

1. Antikinase is a term used in the field of medicine and pharmacology to describe a class of substances or compounds that inhibit the activity of kinases. Kinases are enzymes that play a crucial role in cellular signaling pathways by phosphorylating protein molecules, leading to the regulation of various cellular processes such as cell growth, proliferation, and differentiation.

   Antikinases, also known as kinase inhibitors, work by blocking the binding sites on kinases, preventing their activation and subsequent signaling cascades. This interference with kinase activity can have therapeutic implications, particularly in the treatment of diseases characterized by abnormal kinase signaling, such as cancer and inflammatory disorders.

   Antikinase substances can be classified based on their mechanism of action, such as competitive inhibitors that compete with adenosine triphosphate (ATP) for binding to kinase domains, or non-competitive inhibitors that target allosteric sites on the kinase molecule. Some well-known examples of antikinase drugs include imatinib, dasatinib, and sunitinib, which have been approved for the treatment of certain types of cancer.

   The development of antikinases has opened up new avenues in targeted therapies, allowing for more precise interventions that aim to inhibit specific aberrant kinase signaling pathways while minimizing adverse effects on normal cellular function. These substances hold great promise in personalized medicine, as their utilization can be tailored to the molecular characteristics of individual patients.

2. An antibody to kinase.

   A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.

Common Misspellings for ANTIKINASE

"Antikinase" is a medical term that is derived from two different components: "anti" and "kinase".

The prefix "anti-" comes from the Greek word "antí", meaning "against" or "opposite". It is commonly used in English to indicate an opposition or counteracting action.

The word "kinase" is a noun form of the verb "kinase" combining the Greek root "kinetos", meaning "movement", and the suffix "-ase", which denotes an enzyme. In biochemistry and biology, kinases are enzymes that catalyze the transfer of a phosphate group from adenosine triphosphate (ATP) to specific molecules, a process called phosphorylation.

Therefore, the term "antikinase" refers to a substance or compound that opposes or inhibits the action of kinases, preventing the transfer of phosphate groups and subsequent signaling pathways in cellular processes.

Plural form of ANTIKINASE is ANTIKINASES