CALPACTIN I Meaning and
Definition
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Calpactin I, also known as annexin A2, is a calcium and phospholipid-binding protein that plays a vital role in intracellular calcium signaling, membrane organization, and cellular processes like vesicle trafficking and membrane fusion. It is a member of the annexin protein family.
The protein is composed of two functional domains: an N-terminal domain responsible for calcium-binding and a C-terminal domain involved in phospholipid-binding. Calpactin I specifically binds to negatively charged phospholipids such as phosphatidylserine, mediating their interaction with intracellular membranes. This interaction is crucial for the protein to participate in various cellular events.
One of the most notable functions of calpactin I is its involvement in the regulation of membrane repair. It plays a critical role in the resealing of damaged plasma membranes by interacting with phosphatidylserine exposed on the damaged site. This interaction initiates a cascade of events that leads to membrane resealing and restoration of cell integrity.
Additionally, calpactin I has been implicated in cell migration, invasion, and adhesion. It acts as a link between the cytoskeleton and the plasma membrane, facilitating the movement and attachment of cells. The protein also participates in exocytosis, endocytosis, and phagocytosis, contributing to vesicular trafficking and membrane fusion processes.
Furthermore, calpactin I has been found to be associated with several diseases and conditions, including cancer, osteoarthritis, and autoimmune disorders. Altered expression or dysfunction of this protein has been shown to impact cellular processes and contribute to pathological conditions.
In summary, calpactin I is a calcium and phospholipid-binding protein that functions in the calcium signaling pathway
Common Misspellings for CALPACTIN I
- xalpactin i
- valpactin i
- falpactin i
- dalpactin i
- czlpactin i
- cslpactin i
- cwlpactin i
- cqlpactin i
- cakpactin i
- cappactin i
- caopactin i
- caloactin i
- callactin i
- cal-actin i
- cal0actin i
- calpzctin i
- calpsctin i
- calpwctin i
- calpqctin i
- calpaxtin i
Etymology of CALPACTIN I
The word "Calpactin I" is typically used in the context of biology and refers to a protein complex found in human cells. However, it is important to note that "Calpactin I" is not a specific term or word with etymology in the traditional sense. It is actually a product of an amalgamation of two related terms - "calpactin" and "I" - to describe a specific variant or isoform of the calpactin protein.
The term "calpactin" was coined by researchers studying calcium-binding proteins in the late 1970s. The name "calpactin" is a combination of "calcium" (since these proteins interact with calcium ions) and "actin" (one of the major components of the cell's cytoskeleton).
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