CC CHEMOKINES Meaning and
Definition
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CC Chemokines, also known as C-C motif chemokines, refer to a class of small proteins or peptides that play a significant role in the immune system as chemotactic cytokines. These chemokines belong to the larger chemokine family, which is primarily involved in the regulation of cell trafficking and migration. The "CC" in their name refers to the presence of two adjacent cysteine residues in their amino acid sequence.
CC chemokines act as signaling molecules that orchestrate the movement and positioning of immune cells during various immune responses. They bind to specific receptors on the surface of target cells, activating intracellular signaling pathways and triggering cellular responses. By directing the migration of immune cells, CC chemokines are essential in coordinating immune cell recruitment to inflammation sites and various tissue types.
These chemokines are involved in numerous physiological and pathological processes, including immune cell trafficking, inflammation, wound healing, angiogenesis, and cancer metastasis. They are secreted by a variety of cell types, including immune cells like leukocytes, monocytes, macrophages, and dendritic cells, as well as non-immune cells, such as fibroblasts and endothelial cells.
Notable examples of CC chemokines include MCP-1 (monocyte chemoattractant protein-1), RANTES (regulated upon activation, normal T cell expressed and secreted), MIP-1α (macrophage inflammatory protein-1 alpha), and MIP-1β (macrophage inflammatory protein-1 beta). CC chemokines have been extensively studied due to their crucial role in immune system regulation, and they are promising therapeutic targets for various immune-related diseases and conditions.
Common Misspellings for CC CHEMOKINES
- cc xhemokines
- cc vhemokines
- cc fhemokines
- cc dhemokines
- cc cgemokines
- cc cbemokines
- cc cnemokines
- cc cjemokines
- cc cuemokines
- cc cyemokines
- cc chwmokines
- cc chsmokines
- cc chdmokines
- cc chrmokines
- cc ch4mokines
- cc ch3mokines
- cc chenokines
- cc chekokines
- cc chejokines
- cc chemikines
Etymology of CC CHEMOKINES
The term "CC Chemokines" is derived from the combination of two components: "CC" and "Chemokines".
1. CC: The abbreviation "CC" stands for "Cysteine-Cysteine". It represents a structural motif found in the amino acid sequence of these chemokines. The CC motif refers to the presence of two adjacent cysteine residues near the N-terminus of the protein.
2. Chemokines: Chemokines are a family of small proteins that play a crucial role in immune responses, inflammation, and cell migration. They are involved in directing the movement and positioning of immune cells throughout the body. The term "chemokines" itself comes from the combination of "chemo-" (related to chemical) and "-kines" (derived from the Greek word "kinesis" for movement).
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