CLONAL DELETIONS Meaning and
Definition
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Clonal deletions refer to the loss of a specific segment of DNA within a population of genetically identical cells derived from a single ancestral cell. In biological terms, a clone is a group of cells or organisms that are derived from a single parent cell or individual through asexual reproduction. Deletions, on the other hand, involve the removal or loss of a segment of DNA.
In the context of clonal deletions, a specific segment of DNA is deleted from all the cells within a clonal population, leading to the loss of genetic material. These deletions can occur spontaneously during DNA replication or can be induced by external factors, such as exposure to certain chemicals or radiation.
Clonal deletions can have significant effects on the function and characteristics of the affected cells. Depending on the location and size of the deleted segment, it can result in the loss of vital genes or regulatory elements, which can disrupt normal cellular processes or lead to the development of genetic disorders.
The study of clonal deletions is important in various fields of biology, including genetics, developmental biology, and cancer research. By understanding the mechanisms and consequences of clonal deletions, scientists can gain insights into the role of specific genes and genomic regions in different biological processes. Furthermore, clonal deletions can serve as markers for the identification and characterization of malignant cells in cancer research.
Common Misspellings for CLONAL DELETIONS
- xlonal deletions
- vlonal deletions
- flonal deletions
- dlonal deletions
- ckonal deletions
- cponal deletions
- coonal deletions
- clinal deletions
- clknal deletions
- cllnal deletions
- clpnal deletions
- cl0nal deletions
- cl9nal deletions
- clobal deletions
- clomal deletions
- clojal deletions
- clohal deletions
- clonzl deletions
- clonsl deletions
- clonwl deletions
Etymology of CLONAL DELETIONS
The word "clonal deletions" has its roots in the field of genetics and molecular biology.
The term "clonal" refers to a group of genetically identical cells or individuals that are derived from a single ancestral cell. In genetics, it is used to describe the process of a single cell dividing and giving rise to a population of genetically identical cells.
The term "deletions" refers to the removal or loss of a section of DNA from a chromosome or a gene. It can result in the loss of genetic material, which may have various consequences depending on the specific region affected and the genes involved.
So, when combined, the term "clonal deletions" refers to the occurrence of genetic deletions in a population of genetically identical cells that originate from a single ancestral cell.
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