ENDORIBONUCLEASE H Meaning and
Definition
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Endoribonuclease H, also known as RNase H, is an enzyme that plays a crucial role in nucleic acid metabolism. It is an endoribonuclease that specifically cleaves the RNA portion of RNA-DNA hybrids, which are structures formed when an RNA molecule base pairs with a DNA molecule.
Endoribonuclease H specifically recognizes and cleaves the phosphodiester bond between the RNA strand and its corresponding DNA strand within the RNA-DNA hybrids. This hydrolysis reaction results in the release of a DNA product and a shorter RNA fragment.
This enzyme is essential for various biological processes. During DNA replication, RNA primers synthesized by the enzyme primase are eventually replaced by DNA. Endoribonuclease H is responsible for removing these RNA primers by cleaving the RNA-DNA hybrid, allowing DNA polymerase to fill the gaps with DNA nucleotides.
Endoribonuclease H is also involved in the defense mechanism against viral infections. Many viruses produce RNA-DNA hybrids as part of their replication cycle. The enzyme recognizes and cleaves these hybrids, leading to the degradation of viral RNA, thereby inhibiting the replication process.
In summary, Endoribonuclease H is an enzyme that specifically cleaves the RNA strand within RNA-DNA hybrids. It plays a crucial role in DNA replication, removal of RNA primers, and defense against viral infections.
Common Misspellings for ENDORIBONUCLEASE H
- wndoribonuclease h
- sndoribonuclease h
- dndoribonuclease h
- rndoribonuclease h
- 4ndoribonuclease h
- 3ndoribonuclease h
- ebdoribonuclease h
- emdoribonuclease h
- ejdoribonuclease h
- ehdoribonuclease h
- ensoribonuclease h
- enxoribonuclease h
- encoribonuclease h
- enforibonuclease h
- enroribonuclease h
- eneoribonuclease h
- endiribonuclease h
- endkribonuclease h
- endlribonuclease h
- endpribonuclease h
Etymology of ENDORIBONUCLEASE H
The word "Endoribonuclease H" is derived from the combination of multiple components.
"Endo-" is a prefix in Greek meaning "within" or "internal". In the context of biochemistry, it indicates an enzyme that cleaves within a molecule's structure.
"Ribonuclease" is a compound word consisting of "ribo" and "nuclease". "Ribose" refers to the sugar component found in RNA molecules, while "nuclease" denotes an enzyme that breaks down nucleic acids.
The letter "H" in "Endoribonuclease H" refers to its specific subtype or variant, distinguishing it from other endoribonucleases.
Therefore, "Endoribonuclease H" is an enzyme that specifically cleaves within the structure of RNA molecules and is part of the H subtype or variant of endoribonucleases.
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