ESOMEPRAZOLE Meaning and
Definition
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Esomeprazole is a medication that falls under the category of proton pump inhibitors (PPIs), which are commonly used to reduce the production of stomach acid. It is primarily prescribed for the treatment of conditions related to excessive stomach acid, such as gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
The chemical name for esomeprazole is (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole. It works by selectively binding and inhibiting the enzyme known as the gastric proton pump, which is responsible for the final step in the production of stomach acid. By reducing the production of acid in the stomach, esomeprazole helps to alleviate symptoms such as heartburn, acid reflux, and the healing of damaged esophageal tissue caused by acid exposure.
Esomeprazole is typically available in the form of oral capsules, tablets, or oral suspension. The dosage may vary depending on the specific condition being treated and the severity of symptoms, usually ranging from 20mg to 40mg per day. As with any medication, esomeprazole may have potential side effects, including headache, diarrhea, nausea, abdominal pain, and an increased risk of infections.
It is important to note that esomeprazole should only be used under the guidance and prescription of a healthcare professional, as prolonged use and misuse may have adverse effects. It is recommended to discuss any underlying medical conditions, current medications, or allergies with a healthcare provider before starting esomeprazole.
Etymology of ESOMEPRAZOLE
The word "esomeprazole" is derived from a combination of two elements: "esome" and "prazole".
The first part, "esome", is derived from the chemical compound "S-enantiomer". In chemistry, enantiomers are mirror images of a molecule, which can have different biological activities. Esomeprazole is the S-enantiomer of omeprazole, which is a compound used to reduce stomach acid production.
The second part, "prazole", is a suffix commonly used in the names of proton-pump inhibitors (PPIs), a class of drugs that reduce gastric acid secretion. It has its origins in the drug "omeprazole", the first proton-pump inhibitor discovered.
Therefore, the word "esomeprazole" indicates the specific enantiomer of omeprazole that is used in medicinal formulations.
