FLUORODEOXYURIDINE Meaning and
Definition
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Fluorodeoxyuridine, commonly known as FUDR, is a synthetic anti-cancer drug derived from the nucleoside uridine. It belongs to the class of medications known as antimetabolites, which are substances that interfere with the normal metabolism and function of cells, particularly cancerous cells. FUDR is primarily used in the treatment of various types of cancers, particularly colorectal cancer and liver cancer.
As an antimetabolite, FUDR acts by inhibiting the synthesis of DNA, the genetic material responsible for cell reproduction and growth. It achieves this by being converted into a metabolically active form within the body, which then competes with naturally occurring substances involved in DNA synthesis. This interruption in DNA synthesis impairs the ability of cancer cells to replicate and divide, ultimately leading to their death.
FUDR is generally administered intravenously under the supervision of a healthcare professional, as it can cause side effects such as nausea, vomiting, diarrhea, and bone marrow suppression. Close monitoring of blood counts is often necessary during treatment to ensure appropriate dosages are maintained and to promptly detect any potential adverse effects.
Despite its potential side effects, FUDR has proven to be an effective and valuable tool in the treatment of certain cancers. It is often used in combination with other chemotherapy medications or radiation therapy to enhance the overall effectiveness of cancer treatment strategies. The specific dosage and treatment regimen of FUDR may vary depending on the individual patient, the type and stage of the cancer being treated, and the overall treatment plan determined by the healthcare team.
Common Misspellings for FLUORODEOXYURIDINE
- dluorodeoxyuridine
- cluorodeoxyuridine
- vluorodeoxyuridine
- gluorodeoxyuridine
- tluorodeoxyuridine
- rluorodeoxyuridine
- fkuorodeoxyuridine
- fpuorodeoxyuridine
- fouorodeoxyuridine
- flyorodeoxyuridine
- flhorodeoxyuridine
- fljorodeoxyuridine
- fliorodeoxyuridine
- fl8orodeoxyuridine
- fl7orodeoxyuridine
- fluirodeoxyuridine
- flukrodeoxyuridine
- flulrodeoxyuridine
- fluprodeoxyuridine
- flu0rodeoxyuridine
Etymology of FLUORODEOXYURIDINE
The word "Fluorodeoxyuridine" primarily consists of three parts: "Fluoro-", "deoxy-", and "uridine".
- "Fluoro-" is derived from the chemical element fluorine (symbol: F). It is derived from the Latin word "fluere", meaning "to flow".
- "Deoxy-" is a prefix indicating the absence of oxygen. It is derived from the Greek word "deoxys", meaning "lacking" or "without".
- "Uridine" is derived from the nucleoside of uracil, which is a pyrimidine base commonly found in RNA. It is named after the chemical compound uracil.
Therefore, the word "Fluorodeoxyuridine" refers to a compound that is a derivative of uridine in which a fluorine atom replaces a hydrogen atom on the deoxyribose sugar.
