FOLLICULIN Meaning and
Definition
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Folliculin, also known as FLCN, is a protein encoded by the FLCN gene and plays a crucial role in various cellular processes. It is predominantly found in the cytoplasm of cells, where it interacts with numerous other proteins to regulate key cellular functions.
The function of folliculin is not completely understood, but it is known to be involved in the regulation of cell growth and proliferation. It has been identified as a tumor suppressor gene, meaning that mutations in the FLCN gene can lead to the development of certain types of tumors, primarily in the kidneys and the skin.
Folliculin is also implicated in the regulation of energy metabolism. Studies have shown that it interacts with proteins involved in cellular energy sensing pathways, such as AMP-activated protein kinase (AMPK) and mammalian target of rapamycin complex 1 (mTORC1), which play crucial roles in maintaining cellular energy homeostasis.
Additionally, folliculin has been found to be associated with the regulation of autophagy, a process by which cells recycle components to maintain cellular homeostasis. It interacts with proteins involved in the autophagy pathway and contributes to its proper regulation.
Overall, folliculin is a multifunctional protein involved in various cellular processes, including cell growth, energy metabolism, and autophagy. Its precise mechanisms of action and its involvement in various diseases are areas of ongoing research.
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One of the internal secretions of the ovary which, with lutein and ovulin, constitutes the hormone oophorin.
A practical medical dictionary. By Stedman, Thomas Lathrop. Published 1920.
Common Misspellings for FOLLICULIN
- dolliculin
- colliculin
- volliculin
- golliculin
- tolliculin
- rolliculin
- filliculin
- fklliculin
- fllliculin
- fplliculin
- f0lliculin
- f9lliculin
- fokliculin
- fopliculin
- fooliculin
- folkiculin
- folpiculin
- foloiculin
- folluculin
- folljculin
Etymology of FOLLICULIN
The term "folliculin" does not have a clear or widely recognized etymology. It appears to be a specific term used in medical or scientific contexts related to the study of follicles, particularly in the context of ovarian function. However, it is not commonly found in general language or dictionaries, making it difficult to determine a specific origin or etymology for the word.
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