GRANULOMATOUS CHEILITIS Meaning and
Definition
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Granulomatous cheilitis, also known as Melkersson-Rosenthal syndrome, is a rare chronic inflammatory disorder that primarily affects the lips. It is characterized by the development of recurrent facial swelling, particularly in the upper lip, along with the formation of small, painless, and non-tender granulomas.
Granulomatous cheilitis is believed to be of immunological origin, although its exact cause remains unknown. It is suspected to be an autoimmune condition, as it often coexists with other autoimmune disorders such as Crohn's disease or sarcoidosis. Additionally, genetic factors and bacterial infections have also been suggested as potential triggers.
Symptoms of granulomatous cheilitis typically include episodic lip swelling that may last for hours to days, leading to a swollen appearance. Over time, the recurrent inflammation can result in the formation of non-ulcerated granulomas in the lip tissue. These granulomas may cause cosmetic concerns and functional difficulties, such as difficulty in speaking, eating, and poor oral hygiene maintenance.
Diagnosing granulomatous cheilitis involves a thorough evaluation of the patient's medical history, physical examination, and laboratory tests to rule out other possible causes. Biopsy of the affected tissue may be required for confirmation, revealing the presence of non-caseating granulomas.
Treatment options for granulomatous cheilitis are limited, and the condition can be challenging to manage. Symptomatic treatment includes the use of corticosteroids, either topically or via intralesional injections, to reduce inflammation and swelling. Other medications like non-steroidal anti-inflammatory drugs (NSAIDs) or immune-modulating drugs may be considered in severe cases. Surgical interventions, such as lip reduction surgery, may be performed
Common Misspellings for GRANULOMATOUS CHEILITIS
- franulomatous cheilitis
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- grajulomatous cheilitis
- grahulomatous cheilitis
Etymology of GRANULOMATOUS CHEILITIS
The word "granulomatous" is derived from the Greek words "granulos", meaning "grain" or "seed", and "-oma", meaning "tumor" or "mass". "Cheilitis" comes from the Greek word "cheilos", meaning "lip", with the suffix "-itis", indicating inflammation.
Therefore, "granulomatous cheilitis" describes a condition characterized by the inflammation of the lip, resulting in the formation of granulomas or granulomatous masses.
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