MITOMYCIN C Meaning and
Definition
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Mitomycin C is a highly potent antibiotic and antitumor agent derived from the bacterium Streptomyces caespitosus. It belongs to a class of drugs known as antineoplastic antibiotics, which are used in the treatment of various types of cancer. Mitomycin C exhibits a wide spectrum of activity against both solid tumors and certain blood-related cancers.
As an antibiotic, Mitomycin C works by inhibiting the synthesis of DNA, RNA, and proteins in bacterial cells, thereby preventing their growth and replication. In the context of cancer treatment, this drug acts as a potent DNA crosslinking agent, which means it binds to and inactivates DNA strands, preventing cancer cells from dividing and growing further.
Mitomycin C is commonly used in chemotherapy regimens for the treatment of various cancers, including bladder, stomach, pancreas, lung, breast, and cervix cancers. It can be administered through various routes, such as intravenous, intravesical (directly into the bladder), or intraoperative (during surgical procedures).
However, it is essential to note that Mitomycin C is associated with several side effects, including bone marrow suppression, gastrointestinal disturbances, skin reactions, and kidney toxicity. Close monitoring and proper medical supervision are required during its use to ensure patient safety and optimize treatment outcomes.
Overall, Mitomycin C is a potent antineoplastic antibiotic utilized in cancer treatment, impairing cancer cell growth and replication by interfering with their DNA synthesis and crosslinking.
Common Misspellings for MITOMYCIN C
- nitomycin c
- kitomycin c
- jitomycin c
- mutomycin c
- mjtomycin c
- mktomycin c
- motomycin c
- m9tomycin c
- m8tomycin c
- miromycin c
- mifomycin c
- migomycin c
- miyomycin c
- mi6omycin c
- mi5omycin c
- mitimycin c
- mitkmycin c
- mitlmycin c
- mitpmycin c
- mit0mycin c
Etymology of MITOMYCIN C
The word Mitomycin C is a combination of two parts: mitomycin and the letter C.
Mitomycin is derived from the bacterial species Streptomyces mitoticus, the source of the antibiotic. The name was coined by two of its discoverers, H. Hamaoka and H. Mitsuhashi, in 1958, and it comes from mitos meaning thread or threadlike, and mycin indicating it is an antibiotic.
The letter C stands for the specific version of the compound that was first isolated and identified. It is one of the three major analogs of mitomycin, with the others being Mitomycin A and Mitomycin B.
So, Mitomycin C refers to a derivative of mitomycin, specifically the version labeled as C.
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