OLIGOMYCIN D Meaning and
Definition
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Oligomycin D is a naturally occurring antibiotic that belongs to the macrolide family. It is produced by certain Streptomyces species, particularly Streptomyces diastaticus. Oligomycin D is known for its inhibitory effects on the mitochondrial FoF1-ATP synthase enzyme, which plays a crucial role in the synthesis of ATP (adenosine triphosphate) in cells.
This antibiotic consists of a highly complex structure, comprising several rings and side chains. Its intricate molecular structure accounts for its potent inhibitory activity against the ATP synthase enzyme. Oligomycin D binds to the enzyme at the FO subunit, specifically blocking the H+ ion channel. As a result, the flow of protons through the enzyme is disrupted, which impairs the synthesis of ATP.
Oligomycin D has been extensively studied in the field of biochemistry and cell biology due to its inhibitory action on ATP synthesis. It has proven to be a valuable tool for researchers investigating the importance of ATP in various cellular processes, such as energy metabolism, cell signaling, and cell growth. Furthermore, oligomycin D has been used in cancer research to study the metabolic differences between cancerous cells and healthy cells.
In summary, oligomycin D is a naturally occurring antibiotic that specifically inhibits the mitochondrial ATP synthase enzyme. Its intricate molecular structure and inhibitory properties have made it a valuable compound for studying ATP synthesis and cellular energy metabolism.
Common Misspellings for OLIGOMYCIN D
- iligomycin d
- kligomycin d
- lligomycin d
- pligomycin d
- 0ligomycin d
- 9ligomycin d
- okigomycin d
- opigomycin d
- ooigomycin d
- olugomycin d
- oljgomycin d
- olkgomycin d
- ologomycin d
- ol9gomycin d
- ol8gomycin d
- olifomycin d
- olivomycin d
- olibomycin d
- olihomycin d
- oliyomycin d
Etymology of OLIGOMYCIN D
The word "Oligomycin D" consists of two parts: "oligomycin" and "D".
The term "oligomycin" refers to a class of macrolide antibiotics that are isolated from certain Streptomyces bacteria. These antibiotics were first discovered in the 1950s and are known for their inhibitory effect on the enzyme ATP synthase, which plays a crucial role in the production of energy (ATP) in cells. The word "oligomycin" is derived from the Greek word "oligós", meaning "few" or "small", and the suffix "-mycin", which is used to designate antibiotics.
The letter "D" in "Oligomycin D" simply indicates that it is a specific variant or form of oligomycin. Often, different variations or derivatives of a compound are labeled with letters to distinguish them from each other.
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