How Do You Spell PEPTIDE ELONGATION FACTOR G?

1. Peptide Elongation Factor G (EF-G) is a protein molecule found in prokaryotes that plays a crucial role in protein synthesis. It acts as a molecular motor, facilitating the movement of transfer RNA (tRNA) and ribosome during the translation process.

   During translation, the ribosome reads the genetic information encoded in the messenger RNA (mRNA) and synthesizes a corresponding protein. EF-G is a key component in this process as it assists in the translocation of the ribosome along the mRNA template. It binds to the ribosome, along with a GTP molecule, and helps in shifting the ribosome by one codon, releasing the spent tRNA and allowing a new tRNA to enter and attach to the ribosome. This movement allows the synthesis of a polypeptide chain.

   EF-G is essential for the accuracy and efficiency of protein synthesis. It ensures the correct reading of the mRNA template by coordinating the movement of ribosomes and tRNA through its GTPase activity. Furthermore, EF-G also participates in the proofreading mechanism by hydrolyzing GTP, thereby promoting the proper positioning of the tRNA and maintaining the fidelity of translation.

   The structure and function of EF-G make it a vital component in the protein synthesis machinery of prokaryotes. Its role in promoting efficient and accurate translation makes it a target for antibiotics such as fusidic acid, which inhibit its activity, thereby impairing bacterial protein synthesis and growth.

Common Misspellings for PEPTIDE ELONGATION FACTOR G

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