In medicine and neurology, the term "reaction of degeneration" refers to a characteristic pattern of electrical changes that occur in the nerves and muscles following severe injury or damage to a peripheral nerve. This condition is commonly associated with injuries, trauma, or diseases affecting the nerve roots, plexuses, or peripheral nerves.
The reaction of degeneration is characterized by a specific sequence of changes in the peripheral nerves and muscles. Initially, there is a loss or reduction in the nerve conduction velocity, leading to diminished or absent electrical signals traveling along the affected nerves. This results in a decrease or complete absence of muscle contraction response when the nerve is stimulated.
Over time, the affected muscles may undergo atrophy, as they gradually lose their strength and functionality. In addition, there may be alterations in muscle tone and reflexes due to the disruption of nerve signals.
The reaction of degeneration is considered a sign of severe nerve injury and is often associated with poor prognosis and long-term disability. Diagnosis of this condition is typically made through electrodiagnostic tests such as electromyography and nerve conduction studies.
In summary, the reaction of degeneration is a characteristic sequence of electrical changes that occur in the nerves and muscles following severe peripheral nerve injury. This condition is indicative of severe nerve damage and is associated with muscle weakness, atrophy, and altered reflexes.
