SDHB Meaning and
Definition
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SDHB is an acronym that stands for Succinate Dehydrogenase Complex, Subunit B. It refers to a critical protein component of the succinate dehydrogenase complex, which is an enzyme found in the mitochondria of cells. This enzyme plays a pivotal role in the citric acid cycle, also known as the Krebs cycle, which is an essential part of cellular respiration.
The SDHB protein is responsible for transferring electrons from succinate, a metabolite in the citric acid cycle, to ubiquinone. This transfer of electrons is a crucial step in the production of ATP, the main energy currency of cells. As a subunit of the succinate dehydrogenase complex, SDHB participates in the oxidation-reduction reactions that take place in the inner mitochondrial membrane.
Mutations or alterations in the SDHB gene can result in various health conditions, such as hereditary paraganglioma-pheochromocytoma syndrome and mitochondrial complex II deficiency. These conditions often manifest as tumors in certain areas of the body, such as the adrenal glands or paraganglia. Given its role in energy production and cellular metabolism, any disruption to SDHB function can lead to serious physiological consequences.
In summary, SDHB is a protein subunit found in the succinate dehydrogenase complex, a key enzyme involved in the citric acid cycle and cellular respiration. It plays a crucial role in electron transfer and proper energy production within the mitochondria.
Common Misspellings for SDHB
- zsdhb
- szdhb
- xsdhb
- sxdhb
- sdxhb
- scdhb
- sfdhb
- sdfhb
- sdehb
- sdghb
- sdhgb
- sdnhb
- sdhnb
- sdjhb
- sdhjb
- sduhb
- sdhub
- sdyhb
- sdhvb
- sdhhb
- sdhbg
- s dhb
- sd hb
- sdh b
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