TACHYKININ RECEPTORS Meaning and
Definition
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Tachykinin receptors belong to a class of cell membrane proteins that are part of the larger G-protein-coupled receptor family. These receptors are primarily found in the central and peripheral nervous systems, as well as in various non-neuronal tissues. The term "tachykinin" refers to a family of small peptide neurotransmitters, including substance P, neurokinin A, and neurokinin B, which are known to bind and activate these receptors.
Tachykinin receptors are involved in a wide range of physiological processes, including the modulation of pain, inflammation, neurotransmission, smooth muscle contractions, and the regulation of hormone secretion. There are three main subtypes of tachykinin receptors: NK1, NK2, and NK3. Each of these subtypes exhibits distinct binding affinities for different tachykinin peptides.
NK1 receptors primarily bind substance P and are widely distributed in both the central and peripheral nervous systems. They play a key role in the transmission of pain signals and are implicated in various pathological conditions, such as chronic pain and neurogenic inflammation.
NK2 receptors have a high affinity for neurokinin A and are mainly found in the gastrointestinal tract, where they regulate smooth muscle contractions and secretion of digestive enzymes.
NK3 receptors preferentially bind neurokinin B and are primarily located in the central nervous system, particularly in areas involved in the regulation of hormonal functions.
Understanding the specific roles and mechanisms of tachykinin receptors is crucial for the development of targeted therapeutic interventions for various conditions, including pain management, gastrointestinal disorders, and endocrine dysfunctions.
Common Misspellings for TACHYKININ RECEPTORS
- rachykinin receptors
- fachykinin receptors
- gachykinin receptors
- yachykinin receptors
- 6achykinin receptors
- 5achykinin receptors
- tzchykinin receptors
- tschykinin receptors
- twchykinin receptors
- tqchykinin receptors
- taxhykinin receptors
- tavhykinin receptors
- tafhykinin receptors
- tadhykinin receptors
- tacgykinin receptors
- tacbykinin receptors
- tacnykinin receptors
- tacjykinin receptors
- tacuykinin receptors
- tacyykinin receptors
Etymology of TACHYKININ RECEPTORS
The word "tachykinin receptors" is derived from the Greek words "tachys" meaning "swift" or "fast", and "kinein" meaning "to move". Tachykinins are a family of peptides that are involved in various physiological processes and are known for their ability to elicit rapid responses in cells. Receptors, on the other hand, are proteins present on cell surfaces that bind to specific molecules, such as neurotransmitters or hormones, and trigger a cellular response. Therefore, the term "tachykinin receptors" refers to the receptors that specifically bind to tachykinins and initiate their physiological effects.
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