TETRADECANOYLPHORBOL ACETATE Meaning and
Definition
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Tetradecanoylphorbol acetate (TPA) is a synthetic compound derived from phorbol, a natural compound found in the seed oil of the croton plant. TPA belongs to the class of compounds known as phorbol esters, which are structurally similar to the active component of the irritant resin from poison ivy. TPA has gained significant attention in the fields of medicine and biology due to its numerous pharmacological effects.
At a molecular level, TPA acts as a potent tumor promoter, stimulating the growth and division of cells. It achieves this by activating protein kinase C (PKC), an enzyme involved in various signaling pathways within the cell. PKC activation leads to the modulation of gene expression, increased cell proliferation, and enhanced synthesis of various proteins.
While primarily known for its tumor-promoting properties, TPA also exhibits anti-inflammatory effects by inhibiting the release of pro-inflammatory mediators. Additionally, TPA has been widely used in laboratory research to induce differentiation in various cell types, studying cellular processes, such as apoptosis, cell cycle regulation, and signal transduction.
Despite its diverse pharmacological effects, TPA is not used clinically due to its potential toxic and irritant qualities. It has, however, served as a valuable tool in scientific research, offering insights into cellular mechanisms and facilitating the development of potential therapeutic interventions and drugs targeted at various diseases, including cancer.
Common Misspellings for TETRADECANOYLPHORBOL ACETATE
- retradecanoylphorbol acetate
- fetradecanoylphorbol acetate
- getradecanoylphorbol acetate
- yetradecanoylphorbol acetate
- 6etradecanoylphorbol acetate
- 5etradecanoylphorbol acetate
- twtradecanoylphorbol acetate
- tstradecanoylphorbol acetate
- tdtradecanoylphorbol acetate
- trtradecanoylphorbol acetate
- t4tradecanoylphorbol acetate
- t3tradecanoylphorbol acetate
- terradecanoylphorbol acetate
- tefradecanoylphorbol acetate
- tegradecanoylphorbol acetate
- teyradecanoylphorbol acetate
- te6radecanoylphorbol acetate
- te5radecanoylphorbol acetate
- teteadecanoylphorbol acetate
- tetdadecanoylphorbol acetate
Etymology of TETRADECANOYLPHORBOL ACETATE
The word "Tetradecanoylphorbol Acetate" has a scientific etymology.
- "Tetradecanoyl" is derived from the Latin word "tetradecano", which means a 14-carbon chain. It signifies the presence of a 14-carbon fatty acid (tetradecanoic acid) in the compound.
- "Phorbol" comes from the scientific name of the croton plant (Croton tiglium), which belongs to the genus Phorbol. This compound was initially isolated from this plant.
- "Acetate" indicates the presence of an acetate group in the compound.
Therefore, the name "Tetradecanoylphorbol Acetate" suggests a compound that includes a 14-carbon fatty acid, derived from the croton plant, and containing an acetate group.
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