TOSYL Meaning and
Definition
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Tosyl, also known as p-toluenesulfonyl or tosylate, is a functional group in organic chemistry. It consists of a benzene ring attached to a sulfonic acid group via a sulfur atom. The chemical formula for the tosyl group is C7H7SO2.
Tosyl is commonly used as a protecting group in organic synthesis reactions. It can be easily added or removed without affecting the reactivity of other functional groups present in the molecule. This property makes it useful for protecting alcohols, amines, and other reactive functional groups during specific chemical transformations, as it prevents unwanted reactions and allows for selective reactions to occur.
In addition to its role as a protecting group, tosyl also finds applications as a leaving group in substitution and elimination reactions. The tosylate ion (C7H7SO3-) is an excellent leaving group due to its stability and ability to stabilize the negative charge that forms during the reaction. This stability enhances the reactivity of the compound, making it a valuable tool in various synthetic procedures.
Tosyl compounds are widely utilized in pharmaceutical and biotechnology industries for the synthesis of drugs, agrochemicals, and other fine chemicals. The tosyl group's versatility, stability, and compatibility with various reaction conditions make it a valuable tool in organic chemistry, enabling chemists to perform complex transformations efficiently. Overall, tosyl serves as a versatile and crucial functional group in synthetic organic chemistry.
Common Misspellings for TOSYL
- rosyl
- 6osyl
- 5osyl
- tisyl
- tksyl
- tlsyl
- t0syl
- t9syl
- toayl
- tozyl
- todyl
- toeyl
- towyl
- toshl
- tos7l
- tos6l
- tosyk
- tosyp
- tosyo
- rtosyl
Etymology of TOSYL
The word tosyl is derived from the chemical compound toluenesulfonamide. The toluene part comes from the chemical compound toluene, which is a solvent obtained from coal tar or petroleum that is used in the production of various chemicals. The sulfonamide part indicates that toluene is bonded to a sulfonamide group, which is a functional group containing a sulfur atom bonded to three oxygen atoms and one nitrogen atom. Therefore, the term tosyl is a contraction of toluenesulfonamide.
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