TYROSINE TRANSAMINASE Meaning and
Definition
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Tyrosine transaminase is an enzyme that plays a crucial role in amino acid metabolism. It is also known as tyrosine aminotransferase or tyrosine aminotransferase II. This enzyme belongs to the family of transaminases, which catalyze the transfer of an amino group from an amino acid to a keto acid, resulting in the formation of a new amino acid and a new keto acid.
Specifically, tyrosine transaminase is responsible for the conversion of tyrosine, an aromatic amino acid, into 4-hydroxyphenylpyruvate (4HPP). This reaction involves the transfer of the amino group from tyrosine to alpha-ketoglutarate, which produces 4HPP and glutamate.
The production of 4HPP by tyrosine transaminase is a critical step in the degradation pathway of tyrosine, as it serves as a precursor for the synthesis of important neurotransmitters and hormones, such as dopamine and adrenaline. Therefore, this enzyme is essential for maintaining the normal levels of these neurotransmitters and hormones within the body.
The activity of tyrosine transaminase is regulated by various factors, including the availability of substrates, the presence of coenzymes, and specific cellular signaling pathways. Mutations or dysregulation of this enzyme can lead to metabolic disorders, such as tyrosinemia, which is characterized by the accumulation of toxic metabolites derived from tyrosine, causing severe health complications.
In summary, tyrosine transaminase is an enzyme that catalyzes the conversion of tyrosine to 4HPP, playing a crucial role in the metabolism of tyrosine and the synthesis of neurotransmitters and hormones.
Common Misspellings for TYROSINE TRANSAMINASE
- ryrosine transaminase
- fyrosine transaminase
- gyrosine transaminase
- yyrosine transaminase
- 6yrosine transaminase
- 5yrosine transaminase
- ttrosine transaminase
- tgrosine transaminase
- throsine transaminase
- turosine transaminase
- t7rosine transaminase
- t6rosine transaminase
- tyeosine transaminase
- tydosine transaminase
- tyfosine transaminase
- tytosine transaminase
- ty5osine transaminase
- ty4osine transaminase
- tyrisine transaminase
- tyrksine transaminase
Etymology of TYROSINE TRANSAMINASE
The word "tyrosine" derives from the Greek word "tyros", meaning "cheese". The word "transaminase" consists of the prefix "trans-" meaning "across" or "beyond", and "aminase" which comes from "amine", a compound containing nitrogen. In general, "transaminase" refers to an enzyme that transfers an amino group from one molecule to another. Therefore, "Tyrosine Transaminase" is an enzyme that specifically transfers an amino group to or from tyrosine, likely involved in the metabolism of this particular amino acid.
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