VLP Meaning and
Definition
-
VLP stands for Virus-Like Particle. It is a term used in virology and immunology to describe a type of viral particle that resembles a virus but is non-infectious. VLPs are produced by recombinant DNA techniques or through self-assembly of viral structural proteins in the absence of the viral genome.
VLPs have a similar structure to the actual virus they mimic, including the shape and surface proteins or antigens, but lack the genetic material necessary for replication. These particles can be produced by expressing viral capsid or envelope proteins in a host cell, which then assembles them into empty shells that resemble a virus. Alternatively, VLPs can also be generated by extracting and purifying viral proteins from infected cells.
VLPs have proven to be valuable tools in the development of vaccines, as they can stimulate a specific immune response without causing disease. When VLPs are introduced into the body, the immune system recognizes them as foreign and mounts an immune response, generating antibodies and activating immune cells to fight against the virus-like particles. This immune response can provide protection against future infections by the actual virus, as the body has already developed a defense mechanism.
VLPs have been successfully used for various vaccines against diseases such as hepatitis B, human papillomavirus (HPV), and influenza. Their safety and efficacy make them an attractive alternative to live attenuated or inactivated vaccines, as they can provide similar benefits without the risk of reintroducing the infectious virus.
Common Misspellings for VLP
Infographic
Add the infographic to your website:
