How Do You Spell VON BRAUN AMIDE DEGRADATION?

Pronunciation: [vˈɒn bɹˈɔːn ɐmˈa͡ɪd dɪɡɹɐdˈe͡ɪʃən] (IPA)

The spelling of "von Braun amide degradation" is based on the International Phonetic Alphabet (IPA) transcription system, which represents speech sounds with symbols. The word is pronounced as [vɒn bɹaʊn əmaɪd dɛɡɹədeɪʃən], where each symbol corresponds to a distinct sound. "Von Braun amide degradation" refers to a process by which amide bonds in molecules are cleaved through a reaction facilitated by a catalyst, discovered by the German rocket scientist, Wernher von Braun. Understanding the spelling and pronunciation of scientific terms is important for effective communication and collaboration in the scientific community.

Meaning and Definition
Basic Check Advanced Check

VON BRAUN AMIDE DEGRADATION Meaning and Definition

  1. Von Braun amide degradation, also known as von Braun degradation, refers to a chemical reaction that involves the conversion of an amide compound into a carboxylic acid and an amine through the use of dehydrating agents. This reaction was named after the German chemist Georg von Braun who first described it in the late 19th century.

    The von Braun amide degradation reaction typically proceeds through the following steps: an amide compound reacts with a dehydrating agent, such as concentrated sulfuric acid, to form an imide intermediate. This imide intermediate is further hydrolyzed by water, leading to the formation of a carboxylic acid and an amine. This process involves the breaking of the amide bond (C-N) and the formation of a new carboxylic acid group (C=O) and an amine group (N-H).

    The von Braun amide degradation reaction is commonly employed in organic synthesis as a method for converting amides into their corresponding carboxylic acids and amines. This reaction is useful in the pharmaceutical and chemical industries for the modification of amide-containing compounds, allowing for the synthesis of new compounds with altered properties.

    Overall, von Braun amide degradation is a chemical reaction that involves the transformation of an amide compound into a carboxylic acid and an amine through the use of dehydrating agents, making it a valuable tool in organic synthesis.