NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE Meaning and
Definition
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Nicotinamide Mononucleotide Adenylyltransferase (NMNAT) is an enzyme that plays a crucial role in cellular energy metabolism and the maintenance of nicotinamide adenine dinucleotide (NAD+) levels in the body. NAD+ is a coenzyme involved in several metabolic processes, including the production of energy in the form of adenosine triphosphate (ATP), DNA repair, and regulation of cellular responses to stress and aging.
NMNAT is responsible for catalyzing the production of NAD+ from nicotinamide mononucleotide (NMN), a precursor molecule derived from vitamin B3 (niacin). Through a series of enzymatic reactions, NMNAT transfers an adenylyl group from ATP to NMN, resulting in the formation of NAD+.
Maintaining adequate levels of NAD+ is essential for the proper functioning of many biological processes. NAD+ acts as a critical mediator in the transfer of electrons during energy production, allowing cells to convert nutrients into usable energy. It also serves as a coenzyme for enzymes involved in DNA repair and plays a role in regulating cellular responses to various stresses, such as oxidative stress and inflammation.
Recent research has highlighted the potential importance of NMNAT and NAD+ in combating age-related diseases and promoting longevity. Manipulation of NMNAT levels or increasing NAD+ availability has shown promising effects in animal studies, including improved mitochondrial function, enhanced metabolism, and increased lifespan.
Common Misspellings for NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE
- bicotinamide mononucleotide adenylyltransferase
- micotinamide mononucleotide adenylyltransferase
- jicotinamide mononucleotide adenylyltransferase
- hicotinamide mononucleotide adenylyltransferase
- nucotinamide mononucleotide adenylyltransferase
- njcotinamide mononucleotide adenylyltransferase
- nkcotinamide mononucleotide adenylyltransferase
- nocotinamide mononucleotide adenylyltransferase
- n9cotinamide mononucleotide adenylyltransferase
- n8cotinamide mononucleotide adenylyltransferase
- nixotinamide mononucleotide adenylyltransferase
- nivotinamide mononucleotide adenylyltransferase
- nifotinamide mononucleotide adenylyltransferase
- nidotinamide mononucleotide adenylyltransferase
- nicitinamide mononucleotide adenylyltransferase
- nicktinamide mononucleotide adenylyltransferase
- nicltinamide mononucleotide adenylyltransferase
- nicptinamide mononucleotide adenylyltransferase
- nic0tinamide mononucleotide adenylyltransferase
- nic9tinamide mononucleotide adenylyltransferase
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