THIOREDOXIN M Meaning and
Definition
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Thioredoxin M is a mitochondrial isoform of the protein thioredoxin, which is an essential component of the cellular antioxidant defense system. It functions as a redox-regulating protein involved in maintaining cellular redox homeostasis and protecting cells from oxidative stress.
Thioredoxin M is specifically localized within the mitochondria, the energy-producing organelles of the cell. It plays a crucial role in regulating the redox status of several mitochondrial proteins involved in energy metabolism, as well as in protecting mitochondrial DNA from damage caused by reactive oxygen species.
At the molecular level, thioredoxin M carries out its function by serving as a redox-active disulfide reductase enzyme. It contains a conserved active site motif composed of two cysteine residues that can be oxidized and reduced through reversible disulfide bond formation. This redox cycle enables thioredoxin M to transfer electrons between proteins, facilitating their proper folding, structural maintenance, and enzymatic activity.
In addition to its role in oxidative stress defense, thioredoxin M has been associated with other important cellular processes, including cell growth, apoptosis, and immune response. Its dysregulation has been linked to various diseases, such as cancer, neurodegenerative disorders, and cardiovascular conditions.
In summary, thioredoxin M is a mitochondria-specific protein that acts as a redox regulator to maintain cellular redox balance, protect cells from oxidative damage, and contribute to various cellular processes essential for proper functioning and health.
Common Misspellings for THIOREDOXIN M
- rhioredoxin m
- fhioredoxin m
- ghioredoxin m
- yhioredoxin m
- 6hioredoxin m
- 5hioredoxin m
- tgioredoxin m
- tbioredoxin m
- tnioredoxin m
- tjioredoxin m
- tuioredoxin m
- tyioredoxin m
- thuoredoxin m
- thjoredoxin m
- thkoredoxin m
- thooredoxin m
- th9oredoxin m
- th8oredoxin m
- thiiredoxin m
- thikredoxin m
Etymology of THIOREDOXIN M
The word "thioredoxin" is derived from the combination of two parts: "thio" and "redoxin".
- "Thio" comes from the Greek word "theion", meaning "sulfur". In biology, "thio-" is often used to refer to a sulfur-containing group or compound.
- "Redoxin" is a term commonly used for proteins or enzymes involved in redox reactions. "Redox" is a combination of "reduction" and "oxidation", which are opposite chemical processes involved in electron transfer.
Thus, "thioredoxin" refers to a protein or enzyme containing a sulfur-based group that participates in redox reactions.
The "M" in "Thioredoxin M" likely stands for "Mitochondrial". Mitochondria are known as the powerhouse of the cell, responsible for producing energy through cellular respiration.
Similar spelling words for THIOREDOXIN M
- thyreotoxin, thyrotoxin,
- thioredoxin reductase.
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